Neurology
Services / neurology
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Topical ointments and creams are semi-solid preparations intended for external application to the skin or mucous membranes. They deliver medications directly to the site of action, providing localized treatment with minimal systemic absorption. This method is particularly beneficial for skin conditions but also has applications in treating neurological issues through innovative delivery systems.
How it works:
Types of Topical Preparations: Ointments: Oil-based and greasy, ointments have a high lipid content, making them ideal for dry, scaly skin conditions. They provide an occlusive layer that helps retain moisture. Creams: These are emulsions of oil and water, less greasy than ointments, and easily absorbed by the skin. Creams are suitable for moist or weeping skin conditions. Gels: Clear, jelly-like substances that are non-greasy and quickly absorbed. Gels are often used for their cooling effect. Lotions: Liquid preparations suitable for hairy or large areas of the body. They are easy to spread and absorb quickly. Pastes: Thick mixtures containing a high proportion of solids. Pastes are used for their protective and absorptive properties.
Other Info:
Topical Treatments Related to Brain Conditions.
While traditional topical applications target skin conditions, advancements in pharmaceutical technology have enabled the development of topical and transdermal systems that can affect the brain and nervous system.
Transdermal Drug Delivery Systems: These systems deliver medications through the skin into systemic circulation, potentially reaching the brain. They provide a non-invasive route for administering drugs that treat neurological conditions.
Examples:
Transdermal Patches for Neurological Disorders:
Rotigotine Patches: Used in the management of Parkinson's disease, rotigotine patches provide continuous dopaminergic stimulation to alleviate motor symptoms.
Rivastigmine Patches: Employed in treating Alzheimer's disease, these patches offer steady medication levels to help improve cognitive function.
Key Points:
Reduced Systemic Side Effects: Minimizes gastrointestinal and hepatic first-pass metabolism, lowering the risk of systemic adverse effects.
Steady Medication Levels: Provides controlled release of drugs over extended periods, reducing the frequency of dosing.
Reduced Systemic Side Effects: Minimizes gastrointestinal and hepatic first-pass metabolism, lowering the risk of systemic adverse effects.
